PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-induced hypernociception in rats.
Molecular Weight:
896.09
CAS Number:
[219639-75-5]
Formula:
C47H65N11O7
Target:
Complement System
T28429
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