QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, dose-dependently activating Kv7 currents, enhancing native neuronal M currents, and causing a decrease in evoked action potentials. It has anti-nociceptive effects on inflammatory pain and can be used for neuronal excitability disorders.
Molecular Weight:
443.18
Purity:
99.17%
CAS Number:
[1259536-62-3]
Formula:
C18H8Cl2F4N4O
Target:
Potassium Channel
T28483
T28483
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