SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.
Molecular Weight:
265.31
Purity:
98.40%
CAS Number:
[223788-33-8]
Formula:
C15H15N5
Target:
Others|||Apoptosis|||Src
T28773
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