TP-064 is a potent and selective PRMT4 inhibitor, featuring an IC50 < 10nM for methylation of H3 (1-25) and over 100-fold selectivity compared to other histone methyltransferases and non-epigenetic targets. It inhibits the methylation of MED12 in cells with an IC50 of 43 nM.
Molecular Weight:
458.6
Purity:
99.07%
CAS Number:
[2080306-20-1]
Formula:
C28H34N4O2
Target:
Histone Methyltransferase
T28996
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