ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 (Polycomb Repressive Complex 2) enzymatic activities, exhibiting IC50 values of 5.6, 15, and 4.0 nM, respectively. Additionally, ZLD1039 effectively suppresses breast tumor growth and metastasis.
Molecular Weight:
612.8
Purity:
99.50%
CAS Number:
[1826865-46-6]
Formula:
C36H48N6O3
Target:
Histone Methyltransferase
T29231
* VAT and and shipping costs not included. Errors and price changes excepted
