A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-beta type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.
Molecular Weight:
421.52
Purity:
98.76%
CAS Number:
[909910-43-6]
Formula:
C25H19N5S
Target:
ALK|||TGF-beta/Smad
T3031
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