(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-beta-activated kinase 1 (TAK-1, IC50 = 1.3 µM).1 (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 µM, respectively.2
Molecular Weight:
362.37
CAS Number:
[1198574-97-8]
Formula:
C19H22O7
Target:
Others
T35438
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