alpha-Galactosylceramide analog 8 , alpha-GalCer analog 8
alpha-Galactosylceramide analog 8 (alpha-GalCer analog 8) is a triazole derivative of alpha-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with alpha-GalCer analog 8 at a concentration of 32 ng/ml. alpha-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic alpha-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &181g per animal dose, indicating a Th2 response.
Molecular Weight:
868.339
CAS Number:
[922727-14-8]
Formula:
C50H97N3O8
Target:
Others
T35450
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