(S)-PI3Kalpha-IN-4, a potent inhibitor of PI3Kalpha with an IC50 of 2.3 nM, demonstrates 38.3-, 4.25-, and 4.93-fold selectivity over PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively, and is suitable for cancer research[1]. (S)-PI3Kalpha-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution[1].
Molecular Weight:
560
CAS Number:
[2322293-84-3]
Formula:
C25H23ClFN5O5S
Target:
Others|||PI3K
T35488
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