12-HETE (()12-HETE) is a modulator of PGE2, with both anti-thrombotic and pro-thrombotic effects, inducing PGE2 release and COX-2 expression via phospholipase A2 (sPLA2-IIA) inducers. It is also a neuroregulator activating retinal cell endothelial dysfunction in diabetic retinopathy.
Molecular Weight:
320.47
CAS Number:
[71030-37-0]
Formula:
C20H32O3
Target:
Apoptosis
T35507
T35507
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