Ganglioside GD1a mixture (sodium salt), CAS [[12707-58-3]]

Product Overview

• Article Name: Ganglioside GD1a mixture (sodium salt), CAS [[12707-58-3]]
• Biozol Catalog Number: TGM-T35587
• Supplier Catalog Number: T35587
• Alternative Catalog Number: TGM-T35587-1MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Ganglioside B1

Product Description

Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 µM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin.[2] Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.

Product Properties

• Molecular Weight: 1836.1
• CAS Number: [12707-58-3]
• Formula: C84H146N4O392Na
• Target: Others