Febuxostat Acyl Glucuronide is the primary metabolite of the potent xanthine oxidase (XO) inhibitor Febuxostat. It is formed through the glucuronidation of the carboxylic acid group of Febuxostat, a process mediated by UDP-glucuronosyltransferase (UGT) enzymes. The production of this acyl glucuronide is a major elimination pathway for the parent drug. Researching this metabolite is essential for characterizing metabolic clearance, understanding drug-drug interactions, and evaluating the pharmacokinetic variability of Febuxostat across different patient populations, including those with UGT enzymatic polymorphisms.
Molecular Weight:
492.5
Purity:
98.00%
CAS Number:
[1351692-92-6]
Formula:
C22H24N2O9S
Target:
Drug Metabolite|||Xanthine Oxidase
T35621
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