SR 1903 is an inverse agonist of RORgamma and PPARgamma (IC50 = 100 nM and 209 nM, respectively) and an agonist of LXR (EC50 = 154 nM). It exerts anti-inflammatory and anti-diabetic effects in mouse models of collagen-induced arthritis and diet-induced obesity.
Molecular Weight:
523.51
Purity:
99.93%
CAS Number:
[1414248-06-8]
Formula:
C27H27F6N3O
Target:
ROR|||PPAR|||Liver X Receptor
T35638
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