SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 µM and p-ERK modulation in cells IC50 = 0.250 µM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
Molecular Weight:
352.26
Purity:
99.40%
CAS Number:
[1801747-42-1]
Formula:
C16H19Cl2N5
Target:
Phosphatase|||ERK
T3564
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