Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol. It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 µM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.
Molecular Weight:
412.03
CAS Number:
[17371-30-1]
Formula:
C11H12Br2N2O5
Target:
Others|||Antibacterial
T35651
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