2-Thiouridine (s2U) is a naturally occurring modified nucleobase present in transfer RNAs that stabilizes U:A base pairing while modestly destabilizing U:G wobble interactions. 2-Thiouridine influences codon-anticodon recognition, translational accuracy, and RNA conformational dynamics, and is extensively used in studies of nucleic acid structure, RNA biology, and the engineering of functional RNA-based biomolecules.
Molecular Weight:
260.27
CAS Number:
[20235-78-3]
Formula:
C9H12N2O5S
Target:
Others
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