JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 µg/kg, JMV3002 inhibits hexarelin-stimulated food intake by up to 98% in rats. It does not induce growth hormone release nor inhibit hexarelin-stimulated growth hormone secretion at a dose of 160 µg/kg in infant rats.
Molecular Weight:
586.68
CAS Number:
[925239-03-8]
Formula:
C35H34N6O3
Target:
Others|||GHSR
T35793
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