Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.
Molecular Weight:
320.473
CAS Number:
[183509-23-1]
Formula:
C20H32O3
Target:
Others|||Cytochromes P450
T35848
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