Resolvin E2, CAS [[865532-70-3]]

Product Overview

• Article Name: Resolvin E2, CAS [[865532-70-3]]
• Biozol Catalog Number: TGM-T35881
• Supplier Catalog Number: T35881
• Alternative Catalog Number: TGM-T35881-10UG,TGM-T35881-25UG,TGM-T35881-50UG,TGM-T35881-100UG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in mice fed normal chow, as well as in a mouse model of high-fat diet-induced non-alcoholic fatty liver disease (NAFLD), by dietary supplementation with EPA.4Plasma levels of RvE2 are increased by dietary supplementation with fish oil containing omega-3 polyunsaturated fatty acids (PUFAs) in patients with peripheral artery disease or chronic kidney disease.1,5,6

Product Properties

• Molecular Weight: 334.45
• CAS Number: [865532-70-3]
• Formula: C20H30O4
• Target: Lipoxygenase|||Others

Images

T35881