Penicinoline is an alkaloid that has been found in Penicillium and has antimalarial, insecticidal, and anticancer activities.1,2 It is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50 = 25 µM for both).1 Penicinoline (1,000 ppm) is also active against the aphid A. gossypii.2 It inhibits proliferation of 95-D and HepG2 cancer cells (IC50s = 0.57 and 6.5 µg/ml, respectively) but not HeLa, KB, KBv200, or Hep-2 cells (IC50s = >100 µg/ml).
Molecular Weight:
254.24
CAS Number:
[1214268-60-6]
Formula:
C14H10N2O3
Target:
Others
T35909
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