LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 79 and 763 nM, respectively, in reporter assays).
Molecular Weight:
915.108
CAS Number:
[2375720-38-8]
Formula:
C54H58N8O6
Target:
Others|||PD-1/PD-L1
T36047
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