YW3-56 (hydrochloride) (technical grade), CAS [[2309756-20-3]]

Product Overview

• Article Name: YW3-56 (hydrochloride) (technical grade), CAS [[2309756-20-3]]
• Biozol Catalog Number: TGM-T36108
• Supplier Catalog Number: T36108
• Alternative Catalog Number: TGM-T36108-25MG,TGM-T36108-50MG,TGM-T36108-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: YW3-56 (hydrochloride) (technical grade)

Product Description

YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 µM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 µM) in a p53-dependent mannerviainduction of SESN2 and subsequent inhibition of mTORC1. YW3-56 (10 mg/kg) reduces tumor growth in an S-180 murine sarcoma tumor model. It also inhibits tumor growth in the 1883 MDA-MB-231 breast cancer bone metastasis mouse xenograft model.2

Product Properties

• Molecular Weight: 530.49
• CAS Number: [2309756-20-3]
• Formula: C27H33Cl2N5O2
• Target: mTOR|||PAD|||Others|||MDM-2/p53|||PERK|||Autophagy

Images

T36108