9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1, IC50 = 0.19 µM).1 It decreases LPS- and IFN-gamma-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 µM. 9c(i472) reduces LPS- and IFN-gamma-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 µM.
Molecular Weight:
412.87
CAS Number:
[2349374-37-2]
Formula:
C22H21ClN2O4
Target:
Lipoxygenase|||Others
T36169
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