Globotriaosylceramides (porcine), CAS [[71965-57-6]]
Biozol Catalog Number:
TGM-T36186
Supplier Catalog Number:
T36186
Alternative Catalog Number:
TGM-T36186-1MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme alpha-galactosidase A. Globotriaosylceramides act as natural resistance factors to HIV infection, interacting with HIV gp120 to prevent its interaction with chemokine co-receptors and subsequent fusion of HIV to host cell membranes. This product contains a mixture of hydroxy and non-hydroxy fatty acid-containing globotriaosylceramides isolated from porcine red blood cells (RBCs).
Molecular Weight:
1136.553
CAS Number:
[71965-57-6]
Formula:
C60H113NO18
Target:
HIV Protease|||Others
T36186
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