Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM.
Molecular Weight:
360.49
CAS Number:
[74843-13-3]
Formula:
C22H32O4
Target:
Others|||Prostaglandin Receptor
T36211
* VAT and and shipping costs not included. Errors and price changes excepted
