17R(18S)-EpETE, CAS [[725246-18-4]]

Product Overview

• Article Name: 17R(18S)-EpETE, CAS [[725246-18-4]]
• Biozol Catalog Number: TGM-T36215
• Supplier Catalog Number: T36215
• Alternative Catalog Number: TGM-T36215-50UG,TGM-T36215-100UG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs, EC50= ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4

Product Properties

• Molecular Weight: 318.457
• CAS Number: [725246-18-4]
• Formula: C20H30O3
• Target: Calcium Channel|||Others

Images

T36215