5-cis Carbaprostacyclin, a stable analog of PGI2 and an isomer of carbaprostacyclin, is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 µM compared to 0.3 µM for carbaprostacyclin. It is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 µM compared to 5.9 µM for carbaprostacyclin and even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.
Molecular Weight:
350.49
CAS Number:
[69609-77-4]
Formula:
C21H34O4
Target:
Prostaglandin Receptor|||PPAR|||Others
T36236
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