IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
Molecular Weight:
247.25
Purity:
97.82%
CAS Number:
[23146-22-7]
Formula:
C15H9N3O
Target:
NF-kappaB|||JNK
T3627
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