C8 D-threo Ceramide (d18:1/8:0), CAS [[175892-43-0]]

Product Overview

• Article Name: C8 D-threo Ceramide (d18:1/8:0), CAS [[175892-43-0]]
• Biozol Catalog Number: TGM-T36322
• Supplier Catalog Number: T36322
• Alternative Catalog Number: TGM-T36322-1MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: C8 D-threo Ceramide (d18:1/8:0)

Product Description

C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 17 µM) and induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 ceramide . C8 D-threo Ceramide is a substrate for E. coli diacylglycerol kinase. It activates ceramide-activated protein kinase (CAPK) in U937 cells. C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of ~5 µg/ml.

Product Properties

• Molecular Weight: 425.698
• CAS Number: [175892-43-0]
• Formula: C26H51NO3
• Target: Others|||Apoptosis

Images

T36322