CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excitation/emission maxima of 454/520 nm, respectively. It is selective for nitroreductase over a variety of bioanalytes, including glutathione, ascorbic acid, and reactive oxygen species such as H2O2. CAY10730 (1 µM) has been used to detect hypoxia in A549 human lung carcinoma cells.
Molecular Weight:
481.46
CAS Number:
[2206677-06-5]
Formula:
C28H19NO7
Target:
Others
T36459
* VAT and and shipping costs not included. Errors and price changes excepted
