Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH,) free radicals in a cell-free assay (IC50 = 132.9 µM). Pyranonigrin A (10 µM) suppresses TNF-alpha-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs).
Molecular Weight:
223.184
CAS Number:
[773855-65-5]
Formula:
C10H9NO5
Target:
Others
T36513
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