IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 µM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 µM). It is selective for IL-4 over IL-13 (EC50= 18.2 µM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 µM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.
Molecular Weight:
321.31
Purity:
98.26%
CAS Number:
[1332184-63-0]
Formula:
C18H12FN3O2
Target:
IL Receptor|||Interleukin
T36527
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