Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting signaling pathways and triggers apoptosis in tumor cells, demonstrating antitumor activity[1].
Molecular Weight:
477.51
Purity:
1
CAS Number:
[177262-30-5]
Formula:
C27H27NO7
Target:
Others|||PERK|||Apoptosis
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