A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 µM), an effect that is reduced in the presence of vitamin B6(EC50= <100 µM).
Molecular Weight:
140.142
CAS Number:
[1331754-16-5]
Formula:
C6H8N2O2
Target:
LPL Receptor|||Others
T36833
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