RA375, an inhibitor of RPN13 (26S proteasome regulatory subunit), enhances UPR signaling, ROS production, and apoptosis. Demonstrating ten times the efficacy against cancer lines compared to RA190, RA375 owes its increased activity to nitro ring substituents and the inclusion of a chloroacetamide warhead.
Molecular Weight:
588.99
Purity:
99.56%
CAS Number:
[2649154-57-2]
Formula:
C30H25ClN4O7
Target:
ROS|||Apoptosis|||Proteasome|||Reactive Oxygen Species
T36902
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