17alpha,20beta-Dihydroxy-4-pregnen-3-one (17alpha,20beta-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in female teleost species. For instance, 1 µg/ml of 17alpha,20beta-DHP induces germinal vesicle breakdown in Persian sturgeon oocytes, a key step in maturation. Gonadotropin-releasing hormone and gonadotropins (follicle-stimulating hormone and luteinizing hormone) stimulate the production of 17alpha,20beta-DHP in vivo or in vitro. 17alpha,20beta-DHP also influences spermiation by stimulating milt production at 5 mg/kg in various male teleosts.
Molecular Weight:
332.48
CAS Number:
[1662-06-2]
Formula:
C21H32O3
Target:
Others|||Endogenous Metabolite
T36912
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