PtdIns-(1,2-dioctanoyl) (sodium salt), CAS [[899827-36-2]]
Biozol Catalog Number:
TGM-T36937
Supplier Catalog Number:
T36937
Alternative Catalog Number:
TGM-T36937-1MG,TGM-T36937-100UG,TGM-T36937-500UG
Manufacturer:
TargetMol
Category:
Biochemikalien
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog, compared to naturally-occurring PtdIns, gives it different physical properties including high solubility in aqueous media. PtdIns are phosphorylated to mono- (PtdIns-P, PIP), di- (PtdIns-P2, PIP2), and triphosphates (PtdIns-P3, PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
Molecular Weight:
609.602
CAS Number:
[899827-36-2]
Formula:
C25H47NaO13P
Target:
Others|||P-gp
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