D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 µM and significantly inhibits DNA synthesis at 3 µM.3
Molecular Weight:
511.19
CAS Number:
[139889-65-9]
Formula:
C29H51ClN2O3
Target:
Transferase|||Others
T36974
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