Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.
Molecular Weight:
453.41
CAS Number:
[2320953-89-5]
Formula:
C22H30Cl2N4O2
Target:
Others|||Histone Methyltransferase
T36981
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