4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes). [1][2][3] It demonstrates IC50 values of 1.3, 0.34, 0.99, 78.5, 1.3, and >30 &181M for Nav1.2, Nav1.3, Nav1.4, Nav1.5, Nav1.7, and Nav1.8, respectively.[1]
Molecular Weight:
301.25
CAS Number:
[13072-89-4]
Formula:
C11H15N3O7
Target:
Sodium Channel|||Others
T37093
* VAT and and shipping costs not included. Errors and price changes excepted
