N-methyl Mesoporphyrin IX is a widely used G-quadruplex DNA-specific fluorescent binder that effectively monitors Abeta fibrillation. N-methyl Mesoporphyrin IX is sensitive to G-quadruplex DNA and unreactive to duplex, triplex, and single-stranded forms of DNA. N-methyl Mesoporphyrin IX needs to stack with Abeta assemblies to emit strong fluorescence. Meanwhile N-methyl Mesoporphyrin IX is an in situ inhibitor and ex situ monitor of Abeta amyloid production in vitro and intracellularly.
Molecular Weight:
580.72
CAS Number:
[142234-85-3]
Formula:
C35H40N4O4
Target:
DNA/RNA Synthesis|||Others
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