()8(9)-EpETE (()8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by cytochrome P-450 (CYP450) epoxy synthase, which is specific for glomerular protection, dose-dependently prevents fspf-induced Palb, activation of Ca2+-activated K+ (BKCa) channels, and is used in the study of cardiovascular disease.