TLR4 inhibitor. Inhibits LPS-induced NF-kappaB activation in HEK293 cells (IC50 = 2.4 µg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.
Molecular Weight:
330.23
Purity:
99.07%
CAS Number:
[613263-00-6]
Formula:
C13H13Cl2N3OS
Target:
TLR
T37292
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