TREK1 and TREK2 channel activator (EC50 = 0.76 µM in Rb efflux assay in TREK1-expressing CHO cells). Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity in vitro.
Molecular Weight:
518.45
CAS Number:
[69563-88-8]
Formula:
C27H20F6N2O2
Target:
Others|||Potassium Channel
T37296
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