Ac-ANW-AMC is a fluorogenic substrate for the beta5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence quantifies the activity of the beta5i/LMP7 subunit. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Target:
Others|||Proteasome
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