Ac-PAL-AMC is a fluorogenic substrate for the beta1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can quantify the activity of the beta1i/LMP2 subunit. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm.
Molecular Weight:
498.57
CAS Number:
[1431362-79-6]
Formula:
C26H34N4O6
Target:
Others|||Proteasome
T37421
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