C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-alpha, c-Jun, and NF-kappaB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.
Molecular Weight:
583.98
CAS Number:
[34354-88-6]
Formula:
C36H73NO4
Target:
Endogenous Metabolite|||IL Receptor|||TNF
T37458
T37458
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