Amycolatopsin A is a macrolide polyketide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis(IC50s = 0.4 and 4.4 µM, respectively) but notB. subtilis,S. aureus,E. coli, orP. aeruginosa(IC50s = >30 µM for all). Amycolatopsin A is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 µM, respectively).
Molecular Weight:
1187.421
CAS Number:
[2209112-96-7]
Formula:
C60H98O23
Target:
Antibacterial|||Others
T37539
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