4-Methylumbelliferyl beta-D-Galactopyranoside-6-sulfate (sodium salt), CAS [[206443-06-3]]

Product Overview

• Article Name: 4-Methylumbelliferyl beta-D-Galactopyranoside-6-sulfate (sodium salt), CAS [[206443-06-3]]
• Biozol Catalog Number: TGM-T37566
• Supplier Catalog Number: T37566
• Alternative Catalog Number: TGM-T37566-1MG,TGM-T37566-5MG,TGM-T37566-10MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

4-Methylumbelliferyl beta-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.

Product Properties

• Molecular Weight: 440.35
• CAS Number: [206443-06-3]
• Formula: C16H17NaO11S
• Target: Others

Images

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