4-Methylumbelliferyl 2-sulfamino-2-deoxy-alpha-D-Glucopyranoside (sodium salt), CAS [[460085-45-4]]
Biozol Catalog Number:
TGM-T37568
Supplier Catalog Number:
T37568
Alternative Catalog Number:
TGM-T37568-1MG,TGM-T37568-500UG
Manufacturer:
TargetMol
Category:
Biochemikalien
4-Methylumbelliferyl 2-sulfamino-2-deoxy-alpha-D-Glucopyranoside (4-MU-alpha-GlcNS) is a fluorogenic substrate of heparin sulphamidase. Heparin sulphamidase cleaves 4-MU-alpha-GlcNS to yield 4-MU-alpha-GlcNH2, which is then cleaved by alpha-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm. The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. 4-MU-alpha-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.
Molecular Weight:
439.37
CAS Number:
[460085-45-4]
Formula:
C16H18NNaO10S
Target:
Others
T37568
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